Serious Movies About Drug Addiction and / or Depression?

Question by Kendall: Serious movies about drug addiction and / or depression?
Looking for movies about the following:
Drug Addiction
Troubled Teenagers
Depression

Serious movies only, no comedies.
All recommendations are appreciated.

Best answer:

Answer by Carolina B.
transpointing!!!! ciao manhattan!!!

Answer by waia2000
Requiem for a Dream

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